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Ceftriaxone+disodium Edetate+sulbactam

About Ceftriaxone+disodium Edetate+sulbactam

Ceftriaxone+disodium Edetate+sulbactam belongs to the group of medicines called antibiotics. It is used to treat life-threatening infections caused by gram-negative bacteria. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

Ceftriaxone+disodium Edetate+sulbactam contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate (an Antibiotic Resistance Breaker), and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam work by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Ceftriaxone+disodium Edetate+sulbactam helps treat bacterial infections.

Ceftriaxone+disodium Edetate+sulbactam will be administered by a healthcare professional; do not self-administer. In some cases, Ceftriaxone+disodium Edetate+sulbactam may cause injection site reactions, diarrhoea, rashes, abdominal pain, nausea, and abnormalities in the number of white blood cells and platelets. Most of these side effects of Ceftriaxone+disodium Edetate+sulbactam do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know about your medical and medication history to avoid the occurrence of potential interactions. Ceftriaxone+disodium Edetate+sulbactam should only be given during pregnancy when it clearly necessary. Hence, inform your doctor if you are pregnant, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Ceftriaxone+disodium Edetate+sulbactam therapy against the risks. Breastfeeding should be avoided unless instructed by the doctor. Consumption of alcohol should be avoided while on treatment with Ceftriaxone+disodium Edetate+sulbactam.

Uses of Ceftriaxone+disodium Edetate+sulbactam

Treatment of Bacterial infections

Medicinal Benefits

Ceftriaxone+disodium Edetate+sulbactam contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate, and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone+disodium Edetate+sulbactam is a unique and patented anti-infective product that is primarily used to treat potentially fatal illnesses caused by gram-negative bacteria. Ceftriaxone works by preventing the production of the bacterial cell wall (a protective covering required for survival). As a result, the bacterial cell wall is damaged, and the organism (bacteria) is killed. Disodium Edetate and Sulbactam function by lowering bacterial resistance and increasing Ceftizoxime action against bacteria.

Directions for Use

A healthcare professional will administer Ceftriaxone+disodium Edetate+sulbactam. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ceftriaxone+disodium Edetate+sulbactam

  • Injection site reactions
  • Diarrhoea
  • Rashes
  • Abdominal pain
  • Nausea
  • Abnormalities in the number of white blood cells and platelets

Drug Warnings

It is recommended not to use if you are allergic to any component in Ceftriaxone+disodium Edetate+sulbactam. If you are pregnant or breastfeeding, discuss with your doctor about the risks and benefits before taking Ceftriaxone+disodium Edetate+sulbactam. For effective outcomes, it is recommended that you complete the entire course of Ceftriaxone+disodium Edetate+sulbactam as prescribed by your doctor. If you are received or scheduled for vaccines, inform your doctor before receiving Ceftriaxone+disodium Edetate+sulbactam. Ceftriaxone+disodium Edetate+sulbactam should be used cautiously in people with Clostridium difficile-associated diarrhoea and hyperbilirubinemia (too much bilirubin in the blood), cardiovascular dysfunction, and tuberculosis. So, before taking the Ceftriaxone+disodium Edetate+sulbactam, inform your doctor about all of your medical problems, sensitivities, and medications.

Drug Interactions

Drug-Drug Interaction: Ceftriaxone+disodium Edetate+sulbactam may interact with certain medicines containing calcium (e.g. calcium chloride, calcium gluceptate, calcium gluconate, calcium saccharate), folic acid analogues (e.g. leucovorin, levoleucovorin), immunosuppressive medications (e.g. Mycophenolate mofetil, mycophenolic acid), antiviral medications (e.g. cidofovir, tenofovir) and certain vaccinations (BCG vaccine, Cholera vaccine live, Typhoid vaccine live).

Drug-Food Interaction: Alcohol consumption should be avoided.

Drug-Disease Interaction: Ceftriaxone+disodium Edetate+sulbactam may interact with certain disease conditions, including colitis (inflammation in your colon), cardiovascular dysfunction, tuberculosis, hyperbilirubinemia, liver dysfunctions, biliary obstruction, pancreatitis and seizures. So, inform your doctor about your medical conditions before taking Ceftriaxone+disodium Edetate+sulbactam.

Drug-Drug Interactions Checker List:

  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE
  • CALCIUM SACCHARATE
  • LEUCOVORIN
  • LEVOLEUCOVORIN
  • MYCOPHENOLATE MOFETIL
  • MYCOPHENOLIC ACID
  • CIDOFOVIR
  • TENOFOVIR
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid taking alcohol while using Ceftriaxone+disodium Edetate+sulbactam since it may worsen the disease condition.

    • Safety Warning

      Pregnancy

      caution

      Ceftriaxone+disodium Edetate+sulbactam should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ceftriaxone+disodium Edetate+sulbactam.

    • Safety Warning

      Breast Feeding

      caution

      Inform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.

    • Safety Warning

      Driving

      caution

      Ceftriaxone+disodium Edetate+sulbactam usually does not affect your ability to drive or operate machinery. However, do not drive or operate machinery if you feel sleepy or dizzy after taking medicine.

    • Safety Warning

      Liver

      caution

      Caution should be exercised while using Ceftriaxone+disodium Edetate+sulbactam in patients with liver disease. Inform your doctor before receiving Ceftriaxone+disodium Edetate+sulbactam if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Kidney

      caution

      The use of Ceftriaxone+disodium Edetate+sulbactam is contraindicated in patients with anuria and severe renal dysfunction. Caution should be exercised while using Ceftriaxone+disodium Edetate+sulbactam in patients with mild to moderate kidney disease. Inform your doctor before receiving Ceftriaxone+disodium Edetate+sulbactam if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Children

      caution

      The safety and effectiveness of Ceftriaxone+disodium Edetate+sulbactam in children have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Probiotics should be taken after taking the full course of Ceftriaxone+disodium Edetate+sulbactam to restore healthy bacteria that may have been killed in the intestine. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
    • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
    • Avoid intake of alcoholic beverages with Ceftriaxone+disodium Edetate+sulbactam as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid Ceftriaxone+disodium Edetate+sulbactam in fighting off infections.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with weak immune systems or who are taking immunosuppressive medicine are more prone to bacterial infection.

    FAQs

    Ceftriaxone+disodium Edetate+sulbactam is used to treat Bacterial infections.

    Ceftriaxone+disodium Edetate+sulbactam contains ceftriaxone, Disodium Edetate, and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Ceftriaxone+disodium Edetate+sulbactam helps treat bacterial infections.

    Ceftriaxone+disodium Edetate+sulbactam may cause Clostridium difficile-associated diarrhoea (CDAD). Antibiotic treatment alters the normal flora, leading to overgrowth of Clostridium difficile, which causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you experience prolonged diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    No, it can only be used to treat specific medical diseases, most notably potentially lethal illnesses caused by gram-negative bacteria.

    Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor right away.

    Usually, Ceftriaxone+disodium Edetate+sulbactam starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

    Disodium Edetate is usually contraindicated in patients with active tuberculosis or healed calcified tubercular lesions. Edetate disodium forms stable soluble complexes with calcium. So, inform your doctor before receiving Ceftriaxone+disodium Edetate+sulbactam if you have had tuberculosis.

    Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning to have a baby. Inform your doctor if you are taking any other medicines including supplements or herbal products as Ceftriaxone+disodium Edetate+sulbactam may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

    Ceftriaxone+disodium Edetate+sulbactam is usually administered in a hospital under the doctor’s supervision. Your doctor will decide the dosage and administration.

    Available Medicines for

    Ceftriaxone+disodium Edetate+sulbactam

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